For the first time since 2010, the Cards open with consecutive road games. However, 4 of the season’s final 6 games are at University of Phoenix Stadium including 3 straight at home in weeks 12-14. The last time the Cards played home games in 3 straight weeks was 2011.

The Jaguars and Titans will be facing the Cards for the first time at University of Phoenix Stadium; after that, all 32 NFL teams will have played at least once at the venue that opened in 2006.

The Cards face 5 playoff teams from a year ago (DAL, NYG, SEA, DET, HOU) including 3 that won 10+ games in 2016 (DAL, NYG, SEA).

The Cardinals close the regular season in Seattle where they are 3-1 under Bruce Arians and have won 2 in a row. Since 2013, AZ has as many wins in Seattle (3) as the rest of the NFL combined. Carson Palmer has a 3-0 record there as Cards starting QB.